Bioprocess engineering

The emergence of recombinant DNA and monoclonal antibody technologies has challenged engineers and scientists to develop the methods and facilities required to manufacture, on a commercial scale, the new products derived from biotechnology. This comprehensive handbook offers engineering and science professionals first-hand accounts of practical and prudent solutions to a wide range of production problems from authorities in the field who have successfully met these challenges.

Thirty-one distinguished contributors from the major bioprocess engineering firms, and such biotechnology and pharmaceutical industry leaders as Hybritech, Celltech, Merck, and Lilly focus on the... type of equipment required in a bib processing plant - including fermenters, centrifuges, chromatographic columns, synthesizing and processing equipment, and such support equipment as water systems, steam generators, waste systems, air conditioning, and more... system components - such as the pumps, filters, and valves that are ubiquitous in bioprocess facilities and not limited to certain types of equipment... design issues - covering the planning and design of the entire facility and the requirements of the containment and validation of the process.