Immunoreceptor tyrosine-based inhibition motifs

"Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation." "Because ITIMs regulate biological functions of a variety of cells, this book will be of interest for investigators from a wide array of scientific disciplines. These include biologists and clinicians, such as immunologists, oncologists, allergologists, virologists and scientists studying antigen-, cytokine-, hormone- or growth factor-induced cell activation, proliferation and differentiation." "The volume contains 15 reviews written by authors who all made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties. It constitutes the first synthesis ever published that is specifically devoted to this emerging topic."--BOOK JACKET.