Home › Authors › John R. Vane 👤 John R. Vane 2 books Biography British pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors. Books by John R. Vane Endothelin II Endothelin II 1991 Ciba Foundation symposium, joi Ciba Foundation symposium, jointly with Committee for Symposia on Drug Action, on adrenergic mechanisms 1960